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Phenacetin CAS 62-44

Short Description:

The antipyretic and analgesic effect of phenacetin is similar to “acetylsalicylic acid”. It is mainly used as an antipyretic and analgesic. The effect is slow and long lasting. It has good curative effect on the treatment of headache, neuralgia, arthralgia and fever. , But its anti-rheumatic and anti-inflammatory effects are weak. Excessive doses can cause methemoglobinemia and cause hypoxia in the body. Long-term medication can damage the kidneys and even cause nipple necrosis.


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Application

The antipyretic and analgesic effect of phenacetin is similar to "acetylsalicylic acid". It is mainly used as an antipyretic and analgesic. The effect is slow and long lasting. It has good curative effect on the treatment of headache, neuralgia, arthralgia and fever. , But its anti-rheumatic and anti-inflammatory effects are weak. Excessive doses can cause methemoglobinemia and cause hypoxia in the body. Long-term medication can damage the kidneys and even cause nipple necrosis. It should be used with caution. Due to its toxic side effects and the rapid development of other similar drugs, the drug has ceased to be used alone, but used as a compound preparation for raw materials and other drugs.

Chemical Name Phenacetin
Synonyms Achrocidin;Acetphenetidin;Contradouleur;p-Acetophenetidide;Codempiral;Expand
CAS No. 62-44-2
Molecular Formula C10H13NO2
Molecular Weight 179.21600
PSA 38.33000
LogP 2.11670

Properties

Appearance & Physical State white crystalline powder
Density 1.099 g/cm3
Boiling Point 132 °C / 4mmHg
Melting Point 133-138ºC
Refractive Index 1.505 (20ºC)
Water Solubility 0.076 g/100 mL
Stability Stable. Incompatible with strong oxidizing agents, strong acids.
Storage Condition 2-8ºC

Safety Info

RTECS AM4375000
Safety Statements S45-S53
HS Code 2924291000
WGK Germany 3
Risk Statements R22; R45
Hazard Codes T

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